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Posted Apr 27, 2026

Staff ML Research Scientist, Co-Folding and Affinity

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Job Description: • Drive the research and development of next-generation deep learning models for protein-ligand co-folding and affinity prediction • Bridge from research to commercial utility by equipping SandboxAQ’s software products with advanced predictive capabilities • Bring novel ideas and the content of scientific papers into the ideation, training, and benchmarking of complex models • Act as a technical beacon for the team, representing SandboxAQ scientifically and shaping its vision externally and internally • Mentor junior researchers and collaborate across engineering and product teams to foster a culture of technical rigor and rapid iteration Requirements: • PhD in Computer Science, Computational Chemistry, or a related field • At least 4 years of post-PhD experience, including experience in a professional industry setting • Direct, hands-on experience developing and executing leading-edge co-folding and/or affinity prediction models • Proven excellence in co-folding and/or affinity prediction, as demonstrated by participation in industrial projects and/or academic publications • Experience functioning within a professional software team, including proficiency in Python and modern ML frameworks (PyTorch/JAX) at scale Benefits: • Comprehensive medical, dental, and vision coverage for employees and dependents with generous employer premium contributions • Retirement savings with company matching • Paid parental leave • Inclusive family-building benefits • Flexible paid time off • Company-wide seasonal breaks • Support for flexible work arrangements that enable sustainable performance • Opportunities for continuous learning and growth through on-the-job development, cross-functional collaboration, and access to internal learning and development programs
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